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Surely you've seen cartoons that depict big elephants shrieking in fear from seeing a little mouse. The myth goes all the way back to A.D. 77 and is credited to a Roman philosopher named Pliney, who claimed, "The elephant hates the mouse above all other creatures." Based on relative size between the two animals, this myth seems absurd. Is there any truth to it? Discovery Channel's show MythBusters did a televised experiment with mice and elephants in Cape Town, South Africa to find out.